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• Greatly reduced differentiation time (3-5 days; >20 days elsewhere)

• Contracts upon stimulation

• Forms sarcomeric striations

• High homogeneity (>90% MHC+/DAPI)

• Multinucleate

• Myosin heavy chain+, α-Actinin+

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Can be used to study:

 

• Muscular dystrophies and myopathies

• Sarcopenia

• Muscular Growth and Atrophy

• Neuromuscular and muscular disorders

• Insulin Signaling